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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DLAT
All Species:
19.39
Human Site:
S341
Identified Species:
26.67
UniProt:
P10515
Number Species:
16
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P10515
NP_001922.2
647
68997
S341
Q
P
L
A
P
T
P
S
A
P
C
P
A
T
P
Chimpanzee
Pan troglodytes
XP_522180
647
68973
S341
Q
P
L
A
P
T
P
S
A
P
C
P
A
T
P
Rhesus Macaque
Macaca mulatta
XP_001107013
647
68918
S341
Q
P
L
A
P
T
P
S
A
P
C
P
A
T
P
Dog
Lupus familis
XP_546524
647
68802
S341
Q
P
V
T
P
T
P
S
A
P
R
P
A
T
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8BMF4
642
67923
S340
Q
P
V
A
P
T
P
S
A
A
P
A
G
P
K
Rat
Rattus norvegicus
P08461
632
67147
S331
Q
P
L
A
P
T
P
S
A
A
P
A
G
P
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509202
536
56600
S247
S
K
A
R
L
Y
V
S
P
L
A
R
K
L
A
Chicken
Gallus gallus
XP_417933
681
72018
A370
A
A
L
P
P
Q
P
A
A
P
P
T
P
A
V
Frog
Xenopus laevis
NP_001082239
628
66845
P318
V
A
V
S
T
P
A
P
T
P
S
A
A
P
S
Zebra Danio
Brachydanio rerio
NP_997832
652
69250
A341
P
I
P
A
P
A
A
A
P
A
A
P
A
A
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609118
512
54233
V225
A
A
A
G
T
G
R
V
Y
A
S
P
M
A
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q19749
507
53448
V220
P
H
S
S
S
G
R
V
S
A
S
P
F
A
K
Sea Urchin
Strong. purpuratus
XP_001190217
487
52117
T200
A
A
P
A
A
G
V
T
Q
G
R
V
F
A
S
Poplar Tree
Populus trichocarpa
XP_002303212
512
55370
L225
D
R
T
F
A
S
P
L
A
R
K
L
A
E
D
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q5M729
539
58449
L252
D
R
V
F
A
S
P
L
A
R
K
L
A
E
D
Baker's Yeast
Sacchar. cerevisiae
P12695
482
51800
H195
G
I
S
L
K
D
V
H
G
T
G
P
R
G
R
Red Bread Mold
Neurospora crassa
P20285
458
48601
A171
F
T
G
R
F
Q
T
A
L
E
R
E
P
N
A
Conservation
Percent
Protein Identity:
100
99.2
98.1
89.4
N.A.
85.6
85.1
N.A.
70.3
72
72.8
71.9
N.A.
42
N.A.
41.7
39.8
Protein Similarity:
100
99.2
98.6
92.8
N.A.
90.2
89.6
N.A.
74.5
78.4
82.6
78.9
N.A.
53.9
N.A.
55
54.1
P-Site Identity:
100
100
100
80
N.A.
53.3
60
N.A.
6.6
33.3
13.3
26.6
N.A.
6.6
N.A.
6.6
6.6
P-Site Similarity:
100
100
100
86.6
N.A.
60
60
N.A.
6.6
40
26.6
33.3
N.A.
6.6
N.A.
20
13.3
Percent
Protein Identity:
36.3
N.A.
N.A.
38.6
33.5
36.6
Protein Similarity:
50.2
N.A.
N.A.
53
48.2
48.8
P-Site Identity:
20
N.A.
N.A.
20
6.6
0
P-Site Similarity:
26.6
N.A.
N.A.
33.3
6.6
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
18
24
12
42
18
6
12
18
53
30
12
18
48
30
18
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
18
0
0
0
0
% C
% Asp:
12
0
0
0
0
6
0
0
0
0
0
0
0
0
12
% D
% Glu:
0
0
0
0
0
0
0
0
0
6
0
6
0
12
0
% E
% Phe:
6
0
0
12
6
0
0
0
0
0
0
0
12
0
0
% F
% Gly:
6
0
6
6
0
18
0
0
6
6
6
0
12
6
0
% G
% His:
0
6
0
0
0
0
0
6
0
0
0
0
0
0
0
% H
% Ile:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
6
0
0
6
0
0
0
0
0
12
0
6
0
24
% K
% Leu:
0
0
30
6
6
0
0
12
6
6
0
12
0
6
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
6
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
6
0
% N
% Pro:
12
36
12
6
48
6
53
6
12
36
18
48
12
18
24
% P
% Gln:
36
0
0
0
0
12
0
0
6
0
0
0
0
0
0
% Q
% Arg:
0
12
0
12
0
0
12
0
0
12
18
6
6
0
6
% R
% Ser:
6
0
12
12
6
12
0
42
6
0
18
0
0
0
12
% S
% Thr:
0
6
6
6
12
36
6
6
6
6
0
6
0
24
0
% T
% Val:
6
0
24
0
0
0
18
12
0
0
0
6
0
0
6
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
6
0
0
6
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _